whole-brain modelling

Excitation-Inhibition Balance and Fronto-Limbic Connectivity Distinguish TMS Treatment Outcomes in Refractory Depression

Background: Intermittent theta burst stimulation (iTBS) targeting the left dorsolateral prefrontal cortex (DLPFC) is effective for treatment-resistant depression, but outcomes remain variable. The neurophysiological mechanisms underlying response …

Developmental disinhibition gates language lateralization in childhood

Hemispheric specialization is a hallmark of brain organization, yet how functionally specialized circuits develop remains unclear. In humans, the developmental shift toward left-hemisphere dominance for language offers a well-characterized model for …